CONSTANCES

Cohort of health examination center consultants

Constances monitors 220,000 volunteers using an annual questionnaire, a health examination every 4 years and by annual matching with the old-age insurance and the national health data system (SNDS) databases. Creation of a biobank of 80,000 volunteers. A cohort of 400,000 persons is strictly representative of the eligible population followed in the administrative databases and makes it possible to study the effects of selection.

Key elements

  • Launched in 2012
  • “Generalist” population cohort
  • Representative sample of 220,000 adults affiliated with the general social security scheme, aged 18 to 69 at enrollment
  • Open to the research and public health community

Objectives of the cohorte

Constances is a tool for epidemiological research, due to its size, the particularly comprehensive nature of the system for monitoring and collecting highly diversified information, using several data sources, it is on the scale of the largest cohorts in the world.

Constances is a tool for public health and monitoring, designed to support the public health objectives of the National Health Insurance Fund (CNAM) and the State, in particular through a partnership with Santé Publique France (French Public Health Agency).

Recent publications

List of accessible publications here.

Management and governance

The Constances project, carried out thanks to the participation of the Health Exam Centers, is the subject of a partnership between the University of Paris (UP), the University of Versailles Saint Quentin, the University of Paris-Saclay, the National Institute of Health and Medical Research (Inserm), the National Health Insurance Fund (CNAM), the National Old Age Insurance Fund (Cnav) and the Ministry of Health (Directorate General for Health). It is coordinated by Marie Zins, epidemiologist, research professor at UP.

Terms and conditions of accessing cohort data

  • On a scientific project after evaluation by an international Scientific Advisory Board.
  • Open to industry within the framework of partnerships managed by Inserm Transfert.
  • The data matched to the SNDSs is accessible via the Secure Data Access Center (CASD) platform.

Detailed information