BANCCO+

A CNV database to reduce diagnostic wandering, identify new genes, and expand our knowledge of the human genome

BANCCO+ succeeds the BANCCO project (French National Bank of Constitutional CNVs), which aimed to create a national database of Copy Number Variations (CNVs) identified in patients through Chromosomal Microarray Analysis (CMA).
CNVs refer to gains or losses of chromosomal segments of varying sizes (from a few hundred to several million bases), which can be associated with disease.

Project objectives

The project focuses on diagnosing chromosomal imbalances in patients, particularly those with neurodevelopmental disorders (NDDs).

Today, the collection, annotation, and interpretation of CNVs remain challenging. BANCCO+, in connection with other international initiatives, will provide major support, especially for biologists and clinicians.

Ultimately hosted within the France Cohortes information system, BANCCO+ aims to become the most comprehensive French database on CNVs.

Project governance

BANCCO+ Consortium

  • Scientific Coordinator: Prof. Damien SANLAVILLE, Hospices Civils de Lyon (HCL), Lyon
  • System Development Lead: Prof. Christophe BÉROUD, Aix-Marseille Université (AMU), Marseille
  • Data Collection Lead: Dr. Frédéric BILAN, CHU de Poitiers, Poitiers

A database involving multiple stakeholders

National partners

  Achro-Puce network  

 

  DEFIDIAG, the pilot project for Rare Diseases under the France Médecine Génomique 2025 Plan 

 

   National Association of Molecular Genetics Practitioners 

 

  NGS Diagnostic network 

 

   French Society of Fetal Pathology 

 

   Association of French-speaking Cytogeneticists   

 

 Association of Carriers of Chromosomal Anomalies

Scientific and Ethics Committee

  • Prof. Sylvie JAILLARD, ACLF
  • Prof. Valérie MALAN, Achro-Puce network
  • Dr. Jean MULLER, NGS-Diag network
  • Dr. Amélie PITON, RéDDI network
  • Prof. Jean-François GUERIN, University of Lyon, former President of the HCL Ethics Committee
  • Mrs. Isabelle MARCHETTI-WATERNAUX, President, Association VALENTIN APAC
  • Dr. Sihem KHEDDOUCI, R&D Project Manager, Lyon Ingénierie Projets

Ce projet bénéficie d'une aide de l’État gérée par l'Agence Nationale de la Recherche au titre de France 2030 portant la référence ANR-21-PMRB-0012.

No news has been published for this cohort, you can consult all the news in the spotlight section