PSY-COH
French cohort of patients suffering from bipolar disorder or schizophrenia
PSY-COH is a research project dedicated to the creation of a national cohort on bipolar disorders and schizophrenia. Its aim is to follow people with bipolar disorder or schizophrenia for several years, in order to characterise the stages of the disease and the associated biological markers.
Key elements
- Launched in 2014
- 1,452 patients with psychotic disorders (bipolar disorders and schizophrenia)
Objectives of the cohorte
The main aims of the PSY-COH project are:
- Identify the clinical forms (age of onset, cognitive decline, somatic comorbidities, etc.) of the diseases and validate the different stages in the evolution of the pathology (staging).
- Characterisation of patient trajectories and their evolution through the different stages of the disease, and through behavioural indicators, predictive and prognostic biomarkers.
- Estimating the use of healthcare services, the cost to society and the quality of life of patients suffering from these diseases.
- Improving early diagnosis and prevention of the mental disorders studied by identifying valid biomarkers and biosignatures (construction of bio-banks enabling ancillary research projects to be set up).
- Enable national or international academic collaborators, or industrial partners, to access the cohort or the data collected, and accelerate scientific progress in the study of these pathologies.
PSY-CO is divided into several programmes:
- PSY-COHorte-BP for monitoring patients with bipolar disorder
- PSY-COHorte-SZ for monitoring patients suffering from schizophrenia
Management and governance
PSY-COH is a programme run by the FondaMental Foundation, a scientific cooperation foundation which relies on the national network of FondaMental Expert Centres and a network of research laboratories (Inserm (Institut National de la Santé et de la Recherche Médicale), CEA (Commissariat à l'Energie Atomique et aux Energies), CNRS (Centre National de la Recherche Scientifique), Institut Pasteur, etc.). ), under the direction of Professor Marion Leboyer, Université Paris Est Créteil, AP-HP (Assistance Publique Hôpitaux de Paris), Inserm and the FondaMental Foundation.
Detailed information
No news has been published for this cohort, you can consult all the news in the spotlight section
How to access data
- On request to the Fondation FondaMental
- Completion of an application by the project leader wishing to use the database/biological samples.
- Assessment of the application by the PsyCoh cohort steering committee, which, if it accepts it, informs the project sponsor and draws up a data/biological sample transfer contract.